Disease is Polygenic

Mendelian genetics and humans

Mendel's laws provide a genetic framework for single gene traits and disease

Mendelian inheritance is the exception not the rule in disease genetics

The role of Polygenic Risk Scores

Assessing the clinical utility of PRS

PRS identifies more of the people at risk of cardiovascular disease

New data; new challenges



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Allelica is a Software Genomics Company developing algorithms and digital tools to accelerate the integration of Polygenic Risk Score in the clinical practice