In the fast-paced world of business, ensuring the well-being of employees has become a top priority for innovative employers. A successful wellness program not only fosters a culture of healthier and happier employees, but also yields impressive returns on investment (ROI) for the employer. According to a study done by…

Maintaining a healthy and engaged workforce is a cornerstone of a successful organization. Workplace health programs not only enhance the well-being of employees but also contribute to increased productivity, reduced absenteeism, and a positive company culture. Health perks are now highly valued. According to a study done by Harvard researchers…

George Busby, Allelica CSO & Co-Founder Cardiovascular diseases — a general term for a suite of diseases that affect the heart or blood vessels — account for one in three deaths globally and are a major drain on public health spending. Our risk of cardiovascular disease increases as we age…

George Busby, Allelica CSO & Co-Founder Clinical trials are an essential part of the pharmaceutical industry, but they face many challenges. One of the significant obstacles is the high rate of failure, with over 90% of drug candidates that enter clinical trials ultimately failing to gain regulatory approval. …

Emma Perez, Genetic Counselor A valid question that is often asked when discussing PRS implementation is “how will this information be used in clinical care in the absence of clinical guidelines for PRS”? One approach is to ensure PRS risk information is presented in a way that mirrors the risk…

Emma Perez, Genetic Counselor — This year was kicked off by the publication of the NSGC Practice Resource for Clinical Counseling/Translation of Polygenic Scores, put together by Wand et al. — a stellar team of leaders in the PRS field. …

George Busby, Allelica CSO & Co-Founder We’ve previously written about how you can use Allelica’s DISCOVER software to build new polygenic risk scores (PRS) and to deploy them at scale with PREDICT. While a PRS provides an accurate assessment of someone’s genetic liability of disease, this number on its own…

This week, scientists from the Clinical Genome Resource (ClinGen) Complex Disease Working Group and the Polygenic Score (PGS) Catalog published a paper in Nature introducing the Polygenic Risk Score Reporting Standards (PRS-RS). The work outlines the minimum set of data to allow scores to be faithfully interpreted and transparently evaluated. …

Cardiovascular disease is the leading cause of death worldwide, with recent estimates putting the global death toll at around 18 million each year. It is also a major burden on populations and health systems, contributing to a reduction in the quality of life for millions of people and treatment costs…